Journal article
CD8+ Tc2 cells: underappreciated contributors to severe asthma
- Abstract:
-
The complexity of asthma is underscored by the number of cell types and mediators implicated in the pathogenesis of this heterogeneous syndrome. Type 2 CD4+ T-cells (Th2) and more recently, type 2 innate lymphoid cells dominate current descriptions of asthma pathogenesis. However, another important source of these type 2 cytokines, especially interleukin (IL)-5 and IL-13, are CD8+ T-cells, which are increasingly proposed to play an important role in asthma pathogenesis, because they are abund...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
NIHR Oxford Biomedical Research Centre
More from this funder
Medical Research Council
More from this funder
Bibliographic Details
- Publisher:
- European Respiratory Society Publisher's website
- Journal:
- European Respiratory Review Journal website
- Volume:
- 28
- Issue:
- 154
- Article number:
- 190092
- Publication date:
- 2019-11-20
- Acceptance date:
- 2019-07-29
- DOI:
- EISSN:
-
1600-0617
- ISSN:
-
0905-9180
- Source identifiers:
-
1036062
Item Description
- Keywords:
- Pubs id:
-
pubs:1036062
- UUID:
-
uuid:38870b15-c043-4695-882c-e4d2e54f031e
- Local pid:
- pubs:1036062
- Deposit date:
- 2019-07-29
Terms of use
- Copyright holder:
- ERS
- Copyright date:
- 2019
- Notes:
- Copyright © ERS 2019. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
If you are the owner of this record, you can report an update to it here: Report update to this record