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IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis.

Abstract:

Only around 80% of patients with generalized myasthenia gravis (MG) have serum antibodies to acetylcholine receptor [AChR; acetylcholine receptor antibody positive myasthenia gravis (AChR-MG)] by the radioimmunoprecipitation assay used worldwide. Antibodies to muscle specific kinase [MuSK; MuSK antibody positive myasthenia gravis (MuSK-MG)] make up a variable proportion of the remaining 20%. The patients with neither AChR nor MuSK antibodies are often called seronegative (seronegative MG, SNM...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awn092

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Journal:
Brain : a journal of neurology
Volume:
131
Issue:
Pt 7
Pages:
1940-1952
Publication date:
2008-07-01
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Source identifiers:
148706

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