Journal article
Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication.
- Abstract:
-
CD8-mediated virus inhibition can be detected in HIV-1-positive subjects who naturally control virus replication. Characterizing the inhibitory function of CD8(+) T cells during acute HIV-1 infection (AHI) can elucidate the nature of the CD8(+) responses that can be rapidly elicited and that contribute to virus control. We examined the timing and HIV-1 antigen specificity of antiviral CD8(+) T cells during AHI. Autologous and heterologous CD8(+) T cell antiviral functions were assessed longit...
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- Publication status:
- Published
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- Publisher copy:
- 10.1128/jvi.00437-12
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Authors
Bibliographic Details
- Journal:
- Journal of virology
- Volume:
- 86
- Issue:
- 12
- Pages:
- 6835-6846
- Publication date:
- 2012-06-01
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- Source identifiers:
-
342077
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:342077
- UUID:
-
uuid:3900bd62-8d1b-4f0f-8908-3d6e396e9449
- Local pid:
- pubs:342077
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2012
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