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An observational method for quantifying the behavioural effects of dopamine agonists: contrasting effects of d-amphetamine and apomorphine.

Abstract:

A novael means of measuring and analysing behavioural effects of dopamine agonists is described and illustrated by a comparison of the effects of d-amphetamine and apomorphine in the rat. d-Amphetamine (0--15 mg/kg IP) produced significant dose- and time-dependent changes in responses such as locomotion, rearing and sniffing, but not in licking or gnawing. In contrast, apomorphine (0--5 mg/kg SC) produced significant increases in licking and gnawing, as well as in locomotion and sniffing, but...

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Publication status:
Published

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Publisher copy:
10.1007/bf00433091

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Psychopharmacology
Volume:
69
Issue:
3
Pages:
253-259
Publication date:
1980-01-01
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
Source identifiers:
16783
Language:
English
Keywords:
Pubs id:
pubs:16783
UUID:
uuid:39477dad-600d-458e-a725-1ac5b8f34b46
Local pid:
pubs:16783
Deposit date:
2012-12-19

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