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Journal article

Genomic kinship construction to enhance genetic analyses in the human connectome project data

Abstract:

Imaging genetic analyses quantify genetic control over quantitative measurements of brain structure and function using coefficients of relationship (CR) that code the degree of shared genetics between subjects. CR can be inferred through self‐reported relatedness or calculated empirically using genome‐wide SNP scans. We hypothesized that empirical CR provides a more accurate assessment of shared genetics than self‐reported relatedness. We tested this in 1,046 participants of the Human Connect...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/hbm.24479

Authors


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Role:
Author
ORCID:
0000-0003-3656-4281
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Statistics
Role:
Author
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Publisher:
Wiley Publisher's website
Journal:
Human Brain Mapping Journal website
Volume:
40
Issue:
5
Pages:
1677-1688
Publication date:
2018-11-29
Acceptance date:
2018-11-07
DOI:
EISSN:
1097-0193
ISSN:
1065-9471
Source identifiers:
951296
Language:
English
Keywords:
Pubs id:
pubs:951296
UUID:
uuid:394a4160-cc69-4ce6-8a66-54fae90d5c7c
Local pid:
pubs:951296
Deposit date:
2018-12-10

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