Journal article
Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable
- Abstract:
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Background: The developmental overnutrition hypothesis suggests that greater maternal obesity during pregnancy results in increased offspring adiposity in later life. If true, this would result in the obesity epidemic progressing across generations irrespective of environmental or genetic changes. It is therefore important to robustly test this hypothesis. Methods and Findings: We explored this hypothesis by comparing the associations of maternal and paternal prepregnancy body mass index (BMI...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1371/journal.pmed.0050033
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Authors
Funding
Medical Research Council
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University of Bristol
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Wellcome Trust
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United States National Institutes of Health: National Institute of Diabetes and Digestive and Kidney Diseases
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Medicine Journal website
- Volume:
- 5
- Issue:
- 3
- Article number:
- e33
- Publication date:
- 2008-03-01
- DOI:
- EISSN:
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1549-1676
- ISSN:
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1549-1277
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:3996ffdf-fc92-4cba-b840-ff9899fe9aba
- Local pid:
- ora:2518
- Deposit date:
- 2009-01-09
Related Items
Terms of use
- Copyright holder:
- Lawlor et al
- Copyright date:
- 2008
- Notes:
- Citation: Lawlor, D. A. et al. (2008). 'Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable', PLoS Medicine, 5(3), e33. [Available at http://medicine.plosjournals.org]. © 2008 Lawlor et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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