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Human polymorphism and human-chimpanzee divergence in pseudoautosomal region correlate with local recombination rate.

Abstract:

Previous studies have shown widespread correlation between nucleotide polymorphism and recombination rate, but the cause of this correlation is unresolved. One explanation is that recombination is associated with point mutations, potentially through mutagenic effects of meiotic crossover. This hypothesis predicts that regions of frequent recombination should show both elevated nucleotide diversity within a species and increased nucleotide divergence between species. Here we tested this hypoth...

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Publication status:
Published

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Publisher copy:
10.1016/j.gene.2005.10.020

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Role:
Author
Journal:
Gene
Volume:
368
Issue:
1-2
Pages:
94-100
Publication date:
2006-03-01
DOI:
EISSN:
1879-0038
ISSN:
0378-1119
Source identifiers:
49188
Language:
English
Keywords:
Pubs id:
pubs:49188
UUID:
uuid:39b60b0c-1d6b-4330-bdaa-b113399e97f0
Local pid:
pubs:49188
Deposit date:
2012-12-19

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