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Journal article

Differential roles for cryptochromes in the mammalian retinal clock

Abstract:

Cryptochromes 1 and 2 (CRY1/2) are key components of the negative limb of the mammalian circadian clock. Like many peripheral tissues, Cry1 and -2 are expressed in the retina, where they are thought to play a role in regulating rhythmic physiology. However, studies differ in consensus as to their localization and function, and CRY1 immunostaining has not been convincingly demonstrated in the retina. Here we describe the expression and function of CRY1 and -2 in the mouse retina in both sexes....

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1096/fj.201701165rr

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Funding agency for:
Foster, R
Grant:
BB/I021086/1
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Funding agency for:
Peirson, S
Grant:
BB/I021086/1
Publisher:
Federation of American Society of Experimental Biology Publisher's website
Journal:
FASEB Journal Journal website
Volume:
32
Issue:
8
Pages:
4302-4314
Publication date:
2018-03-21
Acceptance date:
2018-02-26
DOI:
EISSN:
1530-6860
ISSN:
0892-6638
Pmid:
29561690
Language:
English
Keywords:
Pubs id:
pubs:831286
UUID:
uuid:39cf3cff-4c01-404c-955a-84b1d88d40f0
Local pid:
pubs:831286
Deposit date:
2018-04-27

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