Thesis
Role of OX40-OX40L interactions in the immune response to solid organ allografts
- Abstract:
-
Transplantation is the treatment of choice for end stage organ failure however current immunosuppressive therapies whilst effective at preventing acute allograft rejection, fail to prevent late graft loss due to chronic rejection and are associated with an increased risk of infection and malignancy. Therefore there is a clear unmet clinical need for improved strategies to prevent allograft rejection.
OX40 is a member of the TNFR superfamily that has potent costimulatory properties. ...
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Authors
Contributors
+ Jones, N
Division:
MSD
Department:
Surgical Sciences
Role:
Supervisor
+ Wood, K
Division:
MSD
Department:
Surgical Sciences
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2013
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:3a1f1658-eed2-4d5f-9331-d0ed884ec7ca
- Local pid:
- ora:7298
- Deposit date:
- 2013-09-13
Terms of use
- Copyright holder:
- Kinnear, G
- Copyright date:
- 2013
- Notes:
- This thesis is not currently available in ORA.
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