Journal article
Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.
- Abstract:
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BACKGROUND AND AIMS: Chronic hepatitis C is a global health problem with an estimated 170 million HCV infected individuals at risk of progressive liver disease and hepatocellular carcinoma (HCC). Autotaxin (ATX) is a phospholipase with diverse roles in physiological and pathological processes including inflammation and oncogenesis. Clinical studies have reported increased ATX expression in chronic hepatitis C, however, the pathways regulating ATX and its role in the viral life cycle are not w...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 775.5KB)
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- Publisher copy:
- 10.1016/j.jhep.2017.01.009
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Authors
Funding
NIHR Birmingham Liver Biomedical Research Unit
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Medical Research Council
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European Union
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Biotechnology and Biological Sciences Research Council
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Hepatology Journal website
- Volume:
- 66
- Issue:
- 5
- Pages:
- 919-929
- Publication date:
- 2017-01-23
- Acceptance date:
- 2017-01-08
- DOI:
- EISSN:
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1600-0641
- ISSN:
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0168-8278
- Source identifiers:
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675246
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:675246
- UUID:
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uuid:3a419b71-51fb-47d3-b1ea-3cb2ceb98624
- Local pid:
- pubs:675246
- Deposit date:
- 2017-02-03
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2017
- Notes:
- © 2017 Elsevier Ltd. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: 10.1016/j.jhep.2017.01.009
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