Journal article
Requirement of mature dendritic cells for efficient activation of influenza A-specific memory CD8+ T cells.
- Abstract:
-
It is critical to identify the developmental stage of dendritic cells (DCs) that is most efficient at inducing CD8+ T cell responses. Immature DCs can be generated from monocytes with GM-CSF and IL-4, while maturation is accomplished by the addition of stimuli such as monocyte-conditioned medium, CD40 ligand, and LPS. We evaluated the ability of human monocytes and immature and mature DCs to induce CD8+ effector responses to influenza virus Ags from resting memory cells. We studied replicatin...
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- Publication status:
- Published
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- Publisher copy:
- 10.4049/jimmunol.165.3.1182
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Authors
Bibliographic Details
- Journal:
- Journal of Immunology
- Volume:
- 165
- Issue:
- 3
- Pages:
- 1182-1190
- Publication date:
- 2000-08-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
31720
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:31720
- UUID:
-
uuid:3a4d82f4-0f8e-4125-b1c6-bf6148433416
- Local pid:
- pubs:31720
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
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