Thesis
The role of ephrinB2 in hematopoietic stem/progenitor cell differentiation from an arterial hemogenic endothelium
- Abstract:
-
During development, hematopoiesis develops in temporally distinct waves in the yolk sac (YS) and embryo proper, culminating in the emergence of definitive hematopoietic stem cells (HSCs) from the hemogenic endothelium (HE) of the dorsal aorta. The close association of this aortic endothelium with definitive hematopoiesis suggests a functional relationship between arteriogenesis and blood development, but this association is not fully understood. To gain insight into this relationship, we...
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Authors
Contributors
+ Porcher, C
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Supervisor
+ Tosato, G
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Supervisor
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:3a561742-155f-447e-beb6-42ede41d9bb5
- Local pid:
- ora:9164
- Deposit date:
- 2014-10-24
Terms of use
- Copyright holder:
- Chen, I
- Copyright date:
- 2014
- Notes:
- This thesis is not currently available in ORA.
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