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Journal article

TASK-like potassium channels and oxygen sensing in the carotid body.

Abstract:

Chemosensing by type-1 cells of the carotid body involves a series of events which culminate in the calcium-dependent secretion of neurotransmitter substances which then excite afferent nerves. This response is mediated via membrane depolarisation and voltage-gated calcium entry. Studies utilising isolated cells indicates that the membrane depolarisation in response to hypoxia, and acidosis, appears to be primarily mediated via the inhibition of a background K(+)-current. The pharmacological ...

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Publication status:
Published

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Publisher copy:
10.1016/j.resp.2007.02.013

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Respiratory physiology and neurobiology
Volume:
157
Issue:
1
Pages:
55-64
Publication date:
2007-07-01
DOI:
EISSN:
1878-1519
ISSN:
1569-9048
Source identifiers:
312266
Language:
English
Keywords:
Pubs id:
pubs:312266
UUID:
uuid:3a70af6a-7fcb-4e46-b462-31a5051220ed
Local pid:
pubs:312266
Deposit date:
2013-11-17

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