Journal article
Immunogenicity and protective efficacy of mycobacterial DNA vaccines incorporating plasmid-encoded cytokines against Mycobacterium bovis.
- Abstract:
-
DNA-based vaccines, alone or in combination with other sub-unit vaccination regimes, represent an alternative to live mycobacterial vaccines for protective immunization against tuberculosis. Here, we have used a murine immunization or Mycobacterium bovis aerosol challenge model to assess the immunogenicity and protective efficacy of mycobacterial DNA vaccines. Mice that received immunization with DNA constructs encoding M. bovis antigen 85A (Ag85-A) and arget(ESAT-6) produced measurable inter...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Immunology and cell biology
- Volume:
- 88
- Issue:
- 6
- Pages:
- 651-657
- Publication date:
- 2010-08-01
- DOI:
- EISSN:
-
1440-1711
- ISSN:
-
0818-9641
- Source identifiers:
-
67582
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:67582
- UUID:
-
uuid:3ab36547-1bd0-4292-b1d2-2f55dd7db957
- Local pid:
- pubs:67582
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2010
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