Journal article
Single-molecule light-sheet imaging of suspended T cells
- Abstract:
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Adaptive immune responses are initiated by triggering of the T cell receptor. Single-molecule imaging based on total internal reflection fluorescence microscopy at coverslip/basal cell interfaces is commonly used to study this process. These experiments have suggested, unexpectedly, that the diffusional behavior and organization of signaling proteins and receptors may be constrained before activation. However, it is unclear to what extent the molecular behavior and cell state is affected by t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, 6.2MB)
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- Publisher copy:
- 10.1016/j.bpj.2018.02.044
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Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Biophysical Journal Journal website
- Volume:
- 114
- Issue:
- 9
- Pages:
- 2200-2211
- Publication date:
- 2018-05-08
- Acceptance date:
- 2018-02-02
- DOI:
- EISSN:
-
1542-0086
- ISSN:
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0006-3495
- Pmid:
-
29742413
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
848092
- Local pid:
- pubs:848092
- Deposit date:
- 2020-03-08
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2018
- Rights statement:
- © Elsevier 2018.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.bpj.2018.02.044
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