Journal article
Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae
- Abstract:
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The extent to which evolution is constrained by the rate at which horizontal gene transfer (HGT) allows DNA to move between genetic lineages is an open question, which we address in the context of antibiotic resistance in Streptococcus pneumoniae. We analyze microbiological, genomic, and epidemiological data from the largest-to-date sequenced pneumococcal carriage study in 955 infants from a refugee camp on the Thailand-Myanmar border. Using a unified framework, we simultaneously test prior h...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 523.7KB)
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- Publisher copy:
- 10.1126/sciadv.aaz6137
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Authors
Bibliographic Details
- Publisher:
- American Association for the Advancement of Science Publisher's website
- Journal:
- Science Advances Journal website
- Volume:
- 6
- Issue:
- 21
- Article number:
- eaaz6137
- Publication date:
- 2020-05-20
- Acceptance date:
- 2020-03-10
- DOI:
- EISSN:
-
2375-2548
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1106222
- Local pid:
- pubs:1106222
- Deposit date:
- 2020-06-24
Terms of use
- Copyright holder:
- Lehtinen et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S.Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY)
- Licence:
- CC Attribution (CC BY)
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