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Revisiting the role of insulin-like growth factor-I receptor stimulating activity and the apolipoprotein E in Alzheimer’s disease

Abstract:

Background: Alterations in insulin-like growth factor I (IGF-I) signaling have been associated with dementia and Alzheimer's disease (AD). Studies on the association between IGF-I levels and dementia risk have been inconclusive. We reported earlier that higher levels of IGF-I receptor stimulating activity are associated with a higher prevalence and incidence of dementia. Objective: In the present study, we test the robustness of the association between IGF-I receptor stimulating activity and ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fnagi.2019.00020

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Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Aging Neuroscience
Volume:
11
Article number:
20
Publication date:
2019-02-12
Acceptance date:
2019-01-24
DOI:
EISSN:
1663-4365
Pmid:
30809143
Source identifiers:
977462
Language:
English
Keywords:
Pubs id:
pubs:977462
UUID:
uuid:3ae852cd-dadd-4da1-be11-8c56ade627d8
Local pid:
pubs:977462
Deposit date:
2019-11-19

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