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Journal article

Telomere length is a critical determinant for survival in multiple myeloma

Abstract:

The variable clinical outcomes of Multiple Myeloma (MM) patients are incompletely defined by current prognostication tools. We examined the clinical utility of high-resolution telomere length analysis as a prognostic marker in MM. Cohort stratification, using a previously determined length threshold for telomere dysfunction, revealed that patients with short telomeres had a significantly shorter overall survival (P < 0·0001; HR = 3·4). Multivariate modelling using forward selection identif...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/bjh.14643

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Publisher:
Wiley Publisher's website
Journal:
British Journal of Haematology Journal website
Volume:
178
Issue:
1
Pages:
94-98
Publication date:
2017-03-24
Acceptance date:
2016-12-31
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
Pmid:
28342200
Source identifiers:
930215
Language:
English
Keywords:
Pubs id:
pubs:930215
UUID:
uuid:3b69dc21-0e16-4372-8975-df7d0475b6f9
Local pid:
pubs:930215
Deposit date:
2019-02-27

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