Journal article
TILT: a randomized controlled trial of interruption of antiretroviral therapy with or without interleukin-2 in HIV-1 infected individuals.
- Abstract:
-
OBJECTIVE: We aimed to see if structured treatment interruption (STI) could be supported safely with the use of two cycles of IL-2 (4.5 MIU q12h subcutaneously 5 days) before STI to prolong the time before therapy restarted. METHODS: Subjects were randomly allocated to either A - continuous ART; B - continue for 9 weeks, then STI; restart with the same ART when the CD4 count falls below 200 cells; or C - two cycles of IL-2, 8 weeks apart, while still on ART; at week 9 stop ART and use a new c...
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- Publication status:
- Published
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- Publisher copy:
- 10.1097/qad.0b013e3282f511f1
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Bibliographic Details
- Journal:
- AIDS (London, England)
- Volume:
- 22
- Issue:
- 6
- Pages:
- 737-740
- Publication date:
- 2008-03-01
- DOI:
- EISSN:
-
1473-5571
- ISSN:
-
0269-9370
- Source identifiers:
-
65367
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:65367
- UUID:
-
uuid:3bdafa87-d6bd-41f9-834b-95a186194b6d
- Local pid:
- pubs:65367
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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