Journal article icon

Journal article

CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation

Abstract:

Calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) regulates cell and whole-body metabolism and supports tumorigenesis. The cellular impacts of perturbing CAMKK2 expression are, however, not yet fully characterised. By knocking down CAMKK2 levels, we have identified a number of significant subcellular changes indicative of perturbations in vesicle trafficking within the endomembrane compartment. To determine how they might contribute to effects on cell proliferation, we have used p...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/s41419-021-04335-x

Authors


Expand authors...
Publisher:
Springer Nature Publisher's website
Journal:
Cell Death and Disease Journal website
Volume:
12
Article number:
1040
Publication date:
2021-11-01
Acceptance date:
2021-10-19
DOI:
ISSN:
2041-4889
Keywords:
Pubs id:
1206235
Local pid:
pubs:1206235
Deposit date:
2021-11-01

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP