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Thesis

The role of RASSF1A in human embryonic and neural stem cells during differentiation

Abstract:

Stem cells are characterised by their ability to continuously self-renew and differentiate into various lineages. This balance is tightly controlled by intrinsic and extrinsic factors that maintain normal development and tissue homoeostasis. The dysregu- lation of these factors is associated with oncogenesis and is extensively studied in the context of treatment resistance and tumour reoccurrence. Stem and cancer cells share the ability to indefinitely self-renew and therefore it stands to...

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Division:
MSD
Department:
University of Oxford
Role:
Author

Contributors

Department:
University of Oxford
Role:
Supervisor
Cancer Research UK More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:3c6b1ad1-f57f-4b91-9c1d-1aa830a361bf
Deposit date:
2019-07-16

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