Thesis
The role of RASSF1A in human embryonic and neural stem cells during differentiation
- Abstract:
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Stem cells are characterised by their ability to continuously self-renew and differentiate into various lineages. This balance is tightly controlled by intrinsic and extrinsic factors that maintain normal development and tissue homoeostasis. The dysregu- lation of these factors is associated with oncogenesis and is extensively studied in the context of treatment resistance and tumour reoccurrence. Stem and cancer cells share the ability to indefinitely self-renew and therefore it stands to...
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(Dissemination version, pdf, 46.0MB)
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Funding
Cancer Research UK
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- UUID:
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uuid:3c6b1ad1-f57f-4b91-9c1d-1aa830a361bf
- Deposit date:
- 2019-07-16
Terms of use
- Copyright holder:
- Könnig, D
- Copyright date:
- 2017
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