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Red cell transfusion in outpatients with myelodysplastic syndromes: a feasibility and exploratory randomised trial

Abstract:

Optimal red cell transfusion support in myelodysplastic syndromes (MDS) has not been tested and established. The aim of this study was to demonstrate feasibility of recruitment and follow‐up in an outpatient setting with an exploratory assessment of quality of life (QoL) outcomes (EORTC QLQ‐C30 and EQ‐5D‐5L). We randomised MDS patients to standardised transfusion algorithms comparing current restrictive transfusion thresholds (80 g/l, to maintain haemoglobin 85–100 g/l) with liberal threshold...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1111/bjh.16347

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Oxford college:
Wadham College
Role:
Author
ORCID:
0000-0002-7414-4950
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Role:
Author
ORCID:
0000-0001-9698-7185
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Role:
Author
ORCID:
0000-0003-3645-7988
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Australian and New Zealand Society of Blood Transfusion (ANZSBT) More from this funder
Publisher:
Wiley Publisher's website
Journal:
British Journal of Haematology Journal website
Volume:
189
Issue:
2
Pages:
279-290
Publication date:
2020-01-20
Acceptance date:
2019-10-06
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
Pmid:
31960409
Language:
English
Keywords:
Pubs id:
1084451
Local pid:
pubs:1084451
Deposit date:
2020-06-02

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