Journal article
Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching
- Abstract:
-
BACKGROUND: Acetylation of lysine residues in histone tails plays an important role in the regulation of gene transcription. Bromdomains are the readers of acetylated histone marks, and, consequently, bromodomain-containing proteins have a variety of chromatin-related functions. Moreover, they are increasingly being recognised as important mediators of a wide range of diseases. The first potent and selective bromodomain inhibitors are beginning to be described, but the diverse or unknown func...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- Epigenetics and Chromatin Journal website
- Volume:
- 7
- Issue:
- 1
- Pages:
- 14
- Publication date:
- 2014-07-13
- Acceptance date:
- 2014-06-23
- DOI:
- EISSN:
-
1756-8935
- ISSN:
-
1756-8935
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:3cce4511-9b4a-45ba-bf65-5f692e816524
- Local pid:
- pubs:478300
- Source identifiers:
-
478300
- Deposit date:
- 2014-08-15
Terms of use
- Copyright holder:
- Philpott et al
- Copyright date:
- 2014
- Notes:
- © 2014 Philpott et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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