Journal article
Benralizumab for the prevention of COPD exacerbations
- Abstract:
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BACKGROUND
The efficacy and safety of benralizumab, an interleukin-5 receptor alpha–directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) are not known.
METHODS
In the GALATHEA and TERRANOVA trials, we enrolled patients with COPD (at a ratio of approximately 2:1 on the basis of eosinophil count [≥220 per cubic millimeter vs. ≺220 per cubic milli...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 291.1KB)
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- Publisher copy:
- 10.1056/nejmoa1905248
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Authors
Funding
AstraZeneca
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Kyowa Hakko
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Bibliographic Details
- Publisher:
- Massachusetts Medical Society Publisher's website
- Journal:
- New England Journal of Medicine Journal website
- Volume:
- 381
- Issue:
- 11
- Pages:
- 1023-1034
- Publication date:
- 2019-05-20
- Acceptance date:
- 2019-05-16
- DOI:
- ISSN:
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1533-4406 and 0028-4793
- Pmid:
-
31112385
- Source identifiers:
-
1007327
Item Description
- Language:
- English
- Pubs id:
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pubs:1007327
- UUID:
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uuid:3d078cbe-8ab8-4c1a-857a-12f9887d569a
- Local pid:
- pubs:1007327
- Deposit date:
- 2019-06-10
Terms of use
- Copyright holder:
- Massachusetts Medical Society
- Copyright date:
- 2019
- Notes:
- © 2019 Massachusetts Medical Society
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