Journal article
Association of prolactin receptor (PRLR) variants with prolactinomas
- Abstract:
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Prolactinomas are the most frequent type of pituitary tumors, which represent 10–20% of all intracranial neoplasms in humans. Prolactinomas develop in mice lacking the prolactin receptor (PRLR), which is a member of the cytokine receptor superfamily that signals via Janus kinase-2-signal transducer and activator of transcription-5 (JAK2-STAT5) or phosphoinositide 3-kinase-Akt (PI3K-Akt) pathways to mediate changes in transcription, differentiation and proliferation. To elucidate the role of t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 10.2MB)
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(Version of record, pdf, 1.2MB)
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- Publisher copy:
- 10.1093/hmg/ddy396
Authors
Funding
+ National Institute for Health Research
More from this funder
Funding agency for:
Thakker, R
Grant:
Senior Investigator Award (R.V.T.
+ Wellcome Trust
More from this funder
Grant:
106995/Z/15/Z
Senior Investigator Award (R.V.T.
Funding agency for:
Thakker, R
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Human Molecular Genetics Journal website
- Volume:
- 28
- Issue:
- 6
- Pages:
- 1023–1037
- Publication date:
- 2018-11-15
- Acceptance date:
- 2018-11-11
- DOI:
- EISSN:
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1460-2083
- ISSN:
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0964-6906
- Pmid:
-
30445560
Item Description
- Language:
- English
- Pubs id:
-
pubs:944208
- UUID:
-
uuid:3d0ff851-00cd-4820-bbf2-3d4cc2d1621f
- Local pid:
- pubs:944208
- Deposit date:
- 2018-12-07
Terms of use
- Copyright holder:
- Gorvin et al
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 The Authors. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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