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Journal article

Lipid interaction sites on channels, transporters and receptors: recent insights from molecular dynamics simulations

Abstract:

Lipid molecules are able to selectively interact with specific sites on integral membrane proteins, and modulate their structure and function. Identification and characterisation of these sites is of importance for our understanding of the molecular basis of membrane protein function and stability, and may facilitate the design of lipid-like drug molecules. Molecular dynamics simulations provide a powerful tool for the identification of these sites, complementing advances in membrane protein ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bbamem.2016.02.037

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
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Funding agency for:
Sansom, M
Grant:
WT092970
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Funding agency for:
Hedger, G
Publisher:
Elsevier Publisher's website
Journal:
BBA - Biomembranes Journal website
Volume:
1858
Issue:
10
Pages:
2390–2400
Publication date:
2016-03-03
Acceptance date:
2016-03-01
DOI:
ISSN:
0005-2736
Source identifiers:
606868
Keywords:
Pubs id:
pubs:606868
UUID:
uuid:3d7aecf7-481a-41b2-8e0a-537e186b3c54
Local pid:
pubs:606868
Deposit date:
2016-03-01

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