Journal article
Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting
- Abstract:
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Background
Antimalarial clinical efficacy studies for uncomplicated Plasmodium falciparum malaria frequently encounter situations in which molecular genotyping is unable to discriminate between parasitic recurrence, either new infection or recrudescence. The current WHO guideline recommends excluding these individuals with indeterminate outcomes in a complete case (CC) analysis. Data from the four artemisinin-based combination (4ABC) trial was used to compare the perfo... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.1MB)
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(Version of record, pdf, 1.2MB)
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- Publisher copy:
- 10.1186/s12874-019-0856-z
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Authors
Funding
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Medical Research Methodology Journal website
- Volume:
- 19
- Article number:
- 215
- Publication date:
- 2019-11-27
- Acceptance date:
- 2019-10-21
- DOI:
- EISSN:
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1471-2288
- Source identifiers:
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1074954
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:1074954
- UUID:
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uuid:3d92b1a7-e5e7-40e5-8fc8-19fa07f3f9b8
- Local pid:
- pubs:1074954
- Deposit date:
- 2019-11-29
Terms of use
- Copyright holder:
- Dahal, P et al
- Copyright date:
- 2019
- Notes:
- © The Author(s) 2019. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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