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Metabolomics reveals diet-derived plant polyphenols accumulate in physiological bone

Abstract:

Plant-derived secondary metabolites consumed in the diet, especially polyphenolic compounds, are known to have a range of positive health effects. They are present in circulation after ingestion and absorption and can be sequestered into cells within particular organs, but have rarely been investigated systematically in osteological tissues. However, a small number of polyphenols and similar molecules are known to bind to bone. For example alizarin, a plant derived anthraquinone a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41598-019-44390-1

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Oxford college:
Merton College
Role:
Author
ORCID:
0000-0003-4733-1205
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Publisher:
Springer Nature Publisher's website
Journal:
Scientific Reports Journal website
Volume:
9
Article number:
8047
Publication date:
2019-05-29
Acceptance date:
2019-05-16
DOI:
ISSN:
2045-2322
Source identifiers:
999510
Pubs id:
pubs:999510
UUID:
uuid:3db1d60d-fb5f-4f3e-b766-7ab8204f7e45
Local pid:
pubs:999510
Deposit date:
2019-05-20

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