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Linguistic analysis of protein folding

Abstract:

Folding of nascent chains resembles the decoding of spoken language in that information is emitted as a unidirectional, one-dimensional string of elements, with higher structures and long-distance interactions emerging with time. Applying a ‘pseudolinguistic’ analysis of structure to a set of all 36 possible six-stranded antiparallel β-sandwich topologies reveals new order principles and reduces the complexity of this family significantly. The simple connectivity diagrams (‘linguistic trees’)...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/0014-5793(96)00727-2

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author

Contributors

Biotechnology and Biological Sciences Research Council More from this funder
Engineering and Physical Sciences Research Council More from this funder
Medical Research Council More from this funder
Publisher:
Elsevier Publisher's website
Journal:
FEBS Letters Journal website
Volume:
390
Issue:
3
Pages:
249-252
Publication date:
1996-07-01
DOI:
EISSN:
9600-9027
ISSN:
0014-5793
Language:
English
Keywords:
Subjects:
UUID:
uuid:3e03d8cf-5d3d-424f-82a9-cbc34ec89ef3
Local pid:
ora:8511
Deposit date:
2014-06-03

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