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The roles of apoptotic pathways in the low recovery rate after cryopreservation of dissociated human embryonic stem cells

Abstract:

Human embryonic stem (hES) cells have enormous potential for clinical applications. However, one major challenge is to achieve high cell recovery rate after cryopreservation. Understanding how the conventional cryopreservation protocol fails to protect the cells is a prerequisite for developing efficient and successful cryopreservation methods for hES cell lines and banks. We investigated how the stimuli from cryopreservation result in apoptosis, which causes the low cell recovery rate after ...

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Publisher copy:
10.1002/btpr.368

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
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Journal:
Biotechnology Progress
Volume:
26
Issue:
3
Pages:
827-837
Publication date:
2010-05-01
DOI:
EISSN:
1520-6033
ISSN:
8756-7938
Source identifiers:
179050
Language:
English
Keywords:
Pubs id:
pubs:179050
UUID:
uuid:3e2d3189-45b7-4ddd-a187-67162fbf396e
Local pid:
pubs:179050
Deposit date:
2013-11-16

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