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Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio

Abstract:

Objective:We hypothesized that genes within recently identified loci associated with waist-hip ratio (WHR) exhibit fat depot-specific mRNA expression, which correlates with obesity-related traits.Methods:Adipose tissue (AT) mRNA expression of 6 genes (TBX15/WARS2, STAB1, PIGC, ZNRF3 and GRB14) within these loci showing coincident cis-expression quantitative trait loci was measured in 222 paired samples of human visceral (vis) and subcutaneous (sc) AT. The relationship of mRNA expression level...

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Publication status:
Published

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Publisher copy:
10.1038/ijo.2013.56

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Journal:
INTERNATIONAL JOURNAL OF OBESITY
Volume:
38
Issue:
1
Pages:
120-125
Publication date:
2014-01-01
DOI:
EISSN:
1476-5497
ISSN:
0307-0565
Source identifiers:
447233
Language:
English
Keywords:
Pubs id:
pubs:447233
UUID:
uuid:3e48cb4f-9c9f-4235-a5bb-d7f8fb3ad16b
Local pid:
pubs:447233
Deposit date:
2014-05-13

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