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Journal article

Blood pressure in healthy humans is regulated by neuronal NO synthase

Abstract:

NO is physiologically generated by endothelial and neuronal NO synthase (nNOS) isoforms. Although nNOS was first identified in brain, it is expressed in other tissues, including perivascular nerves, cardiac and skeletal muscle. Increasing experimental evidence suggests that nNOS has important effects on cardiovascular function, but its composite effects on systemic hemodynamics in humans are unknown. We undertook the first human study to assess the physiological effects of systemic nNOS inhib...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/HYPERTENSIONAHA.116.08792

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Publisher:
American Heart Association Publisher's website
Journal:
Hypertension Journal website
Volume:
69
Issue:
5
Pages:
970-976
Publication date:
2017-03-06
Acceptance date:
2017-01-10
DOI:
EISSN:
1524-4563
ISSN:
0194-911X
Pmid:
28264923
Source identifiers:
685363
Language:
English
Keywords:
Pubs id:
pubs:685363
UUID:
uuid:3e770bb7-6192-4238-a6d6-0226a781f162
Local pid:
pubs:685363
Deposit date:
2019-02-08

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