Blood pressure in healthy humans is regulated by neuronal NO synthase
NO is physiologically generated by endothelial and neuronal NO synthase (nNOS) isoforms. Although nNOS was first identified in brain, it is expressed in other tissues, including perivascular nerves, cardiac and skeletal muscle. Increasing experimental evidence suggests that nNOS has important effects on cardiovascular function, but its composite effects on systemic hemodynamics in humans are unknown. We undertook the first human study to assess the physiological effects of systemic nNOS inhib...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
(Version of record, pdf, 261.2KB)
- Publisher copy:
- Copyright holder:
- Shabeeh et al
- Copyright date:
Copyright © 2017 The Authors.
Hypertension is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record