Journal article
Increased frequency of travel in the presence of cross-immunity may act to decrease the chance of a global pandemic
- Abstract:
-
The high frequency of modern travel has led to concerns about a devastating pandemic since a lethal pathogen strain could spread worldwide quickly. Many historical pandemics have arisen following pathogen evolution to a more virulent form. However, some pathogen strains invoke immune responses that provide partial cross-immunity against infection with related strains. Here, we consider a mathematical model of successive outbreaks of two strains—a low virulence (LV) strain outbreak followed by...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Royal Society Publisher's website
- Journal:
- Philosophical Transactions B: Biological Sciences Journal website
- Volume:
- 374
- Issue:
- 1775
- Article number:
- 20180274
- Publication date:
- 2019-05-06
- Acceptance date:
- 2019-05-01
- DOI:
- EISSN:
-
1471-2970
- ISSN:
-
0962-8436
Item Description
- Keywords:
- Pubs id:
-
pubs:996415
- UUID:
-
uuid:3e875e6e-421d-4d8e-a1ab-8802e5eecaae
- Local pid:
- pubs:996415
- Source identifiers:
-
996415
- Deposit date:
- 2019-05-07
Terms of use
- Copyright holder:
- Thompson et al
- Copyright date:
- 2019
- Notes:
- Copyright © 2019 The Authors. Published by the Royal Society. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from The Royal Society at: https://doi.org/10.1098/rstb.2018.0274
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