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Investigating the function of Drosophila MAPs Msd1 and dTD-60 in mitotic spindle assembly

Abstract:

Mitosis is the process by which new cells are formed. Following accurate duplication of chromosomes, a cell must segregate its chromosomes into separate daughter cells with great accuracy. Failure to do so can result in genomic instability. Thus, entry into mitosis is tightly regulated via complex protein interactions. Microtubules (MTs) are versatile Tubulin polymers that constitute a considerable portion of the cytoskeleton, and it is the dramatic rearrangement of MTs upon mitotic entry ...

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Oxford college:
Keble College
Role:
Author

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Division:
MPLS
Department:
Zoology
Role:
Supervisor
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:3ed4021f-2ccc-4821-b7c5-40b06d5639b7
Local pid:
ora:5207
Deposit date:
2011-04-04

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