Journal article
Mix and match: phenotypic coexistence as a key facilitator of cancer invasion
- Abstract:
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Invasion of healthy tissue is a defining feature of malignant tumours. Traditionally, invasion is thought to be driven by cells that have acquired all the necessary traits to overcome the range of biological and physical defences employed by the body. However, in light of the ever-increasing evidence for geno- and phenotypic intra-tumour heterogeneity, an alternative hypothesis presents itself: could invasion be driven by a collection of cells with distinct traits that together facilitate the...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, 4.7MB)
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- Publisher copy:
- 10.1007/s11538-019-00675-0
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Funding
Bibliographic Details
- Publisher:
- Springer Publisher's website
- Journal:
- Bulletin of Mathematical Biology Journal website
- Volume:
- 82
- Issue:
- 1
- Article number:
- 15
- Publication date:
- 2020-01-17
- Acceptance date:
- 2019-12-03
- DOI:
- EISSN:
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1522-9602
- ISSN:
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0092-8240
- Source identifiers:
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1048779
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1048779
- UUID:
-
uuid:3eefa64e-45e4-4204-94c6-8d7d013b5da0
- Local pid:
- pubs:1048779
- Deposit date:
- 2019-12-03
Terms of use
- Copyright holder:
- Strobl, MAR et al
- Copyright date:
- 2020
- Rights statement:
- © The Author(s) 2020. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
- Licence:
- CC Attribution (CC BY)
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