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Journal article

Multi-layered Gag-specific immunodominant responses contribute to improved viral control in the CRF01_AE subtype of HIV-1-infected MSM subjects

Abstract:

The purpose of this study was to characterize specific cytotoxic T-cell (CTL) responses in men who have sex with men (MSM) subjects infected with the human immunodeficiency virus type 1 (HIV-1) CRF01_AE subtype during the first year of infection and impacts on viral control and evolution.Fifteen HIV-1 primary infected cases were recruited from Liaoning MSM prospective cohort. CTL responses to Gag, Pol and Nef proteins at 3 month and 1 year post infection were detected with Gamma interferon en...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12865-016-0166-8

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Grant:
MR/L018942/1
G0600520
G1001046
National Natural Science Foundation of China More from this funder
Ministry of Education, China More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Immunology Journal website
Volume:
17
Pages:
28
Publication date:
2016-08-30
Acceptance date:
2016-08-20
DOI:
EISSN:
1471-2172
ISSN:
1471-2172
Pmid:
27577610
Source identifiers:
641901
Language:
English
Keywords:
Pubs id:
pubs:641901
UUID:
uuid:3f01ccad-46d2-48e5-91ed-1f75256a055e
Local pid:
pubs:641901
Deposit date:
2017-09-07

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