Journal article
CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer.
- Abstract:
-
Human papilloma virus (HPV)-induced cervical cancer constitutively expresses viral E6/E7 oncoproteins and is an excellent target for T cell-based immunotherapy. However, not all tumor-infiltrating T cells confer equal benefit to patients, with epithelial T cells being superior to stromal T cells. To assess whether the epithelial T cell biomarker CD103 could specifically discriminate the beneficial antitumor T cells, association of CD103 with clinicopathological variables and outcome was analy...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Dutch Cancer Society
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Jan Kornelis de Cock Stichting
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Academy of Medical Sciences
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Netherlands Organisation for Scientific Research
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Oxford Cancer Center
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Bibliographic Details
- Publisher:
- Taylor and Francis Publisher's website
- Journal:
- Oncoimmunology Journal website
- Volume:
- 6
- Issue:
- 9
- Pages:
- e1338230
- Publication date:
- 2017-07-01
- Acceptance date:
- 2017-05-30
- DOI:
- EISSN:
-
2162-402X
- ISSN:
-
2162-4011
- Pmid:
-
28932636
- Source identifiers:
-
730849
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:730849
- UUID:
-
uuid:3f2c5b6f-329b-49fb-a911-eef10dfcab0a
- Local pid:
- pubs:730849
- Deposit date:
- 2017-10-13
Terms of use
- Copyright holder:
- Church et al
- Copyright date:
- 2017
- Notes:
-
© 2017 Fenne L. Komdeur, Thalina M. Prins, Stephanie van de Wall, Annechien Plat, G. Bea A. Wisman, Harry Hollema, Toos Daemen, David N. Church, Marco de Bruyn and Hans W. Nijman. Published with license by Taylor and Francis. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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