Thesis
Structure-function studies of the bacterial dsDNA translocase FtsK
- Abstract:
-
DNA translocases are molecular motors that use energy from nucleotide triphosphate (NTP) hydrolysis to move along, pump, remodel or clear DNA. Unlike helicases, double-stranded DNA (dsDNA) translocases do not unwind DNA; their action has no net product apart from inducing supercoils as a result of groove-tracking, which has hampered their characterisation. Many dsDNA translocases appear to have biased directionality. However, the inherent symmetry of dsDNA requires that translocase activit...
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Authors
Contributors
+ Sherratt, D
Division:
MSD
Department:
Biochemistry
Role:
Supervisor
+ Turberfield, A
Division:
MSD
Department:
Biochemistry
Role:
Supervisor
Funding
Bibliographic Details
- Publication date:
- 2010
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:3f4d5ee0-09fa-482b-a90c-62f3acfc788b
- Local pid:
- ora:11600
- Deposit date:
- 2015-06-08
Terms of use
- Copyright holder:
- James Edward Graham
- Copyright date:
- 2010
- Notes:
- This thesis is not currently available in ORA
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