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Effect of elevated glucose on primary human tenocytes and implications for diabetic tendinopathy

Abstract:

Diabetes mellitus (DM) is associated with a variety of musculoskeletal manifestations, including tendinopathy. The incidence of tendon disease in DM patients is increased compared to the general population, suggesting that tendon is a tissue sensitive to elevated blood glucose. Furthermore, it has been shown that chronic high blood glucose levels cause damage to cells in several ways, including increased oxidative stress. Therefore cellular responses of in vitro primary human...

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MSD
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Author

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Orthopaedic Research UK More from this funder
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
UUID:
uuid:3f687e44-2907-4481-9528-b5467aaa7145
Deposit date:
2017-09-29

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