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Journal article

Four ways to fit an ion channel model

Abstract:

Mathematical models of ionic currents are used to study the electrophysiology of the heart, brain, gut, and several other organs. Increasingly, these models are being used predictively in the clinic, for example to predict the risks and results of genetic mutations, pharmacological treatments or surgical procedures. These safety-critical applications depend on accurate characterisation of the underlying ionic currents. Four different methods can be found in the literature to fit voltage-sensi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bpj.2019.08.001

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Computer Science
Role:
Author
ORCID:
0000-0003-4062-3061
More by this author
Institution:
University of Oxford
Department:
Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Computer Science
Role:
Author
Publisher:
Cell Press Publisher's website
Journal:
Biophysical Journal Journal website
Volume:
117
Issue:
12
Pages:
2420-2437
Publication date:
2019-08-06
Acceptance date:
2019-08-01
DOI:
EISSN:
1542-0086
ISSN:
0006-3495
Source identifiers:
1037217
Language:
English
Pubs id:
pubs:1037217
UUID:
uuid:3fa8a180-3530-4932-b4a1-8c8148756347
Local pid:
pubs:1037217
Deposit date:
2019-08-19

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