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In situ macromolecular crystallography using microbeams

Abstract:

Despite significant progress in high-throughput methods in macromolecular crystallography, the production of diffraction-quality crystals remains a major bottleneck. By recording diffraction in situ from crystals in their crystallization plates at room temperature, a number of problems associated with crystal handling and cryoprotection can be side-stepped. Using a dedicated goniometer installed on the microfocus macromolecular crystallography beamline I24 at Diamond Light Source, crystals ha...

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Publisher copy:
10.1107/S0907444912006749

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Author
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Journal:
Acta Crystallographica Section D: Biological Crystallography
Volume:
68
Issue:
5
Pages:
592-600
Publication date:
2012-05-01
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
Source identifiers:
329403
Pubs id:
pubs:329403
UUID:
uuid:3fc01646-458c-43e3-86af-f7ebb8b4dfd8
Local pid:
pubs:329403
Deposit date:
2012-12-19

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