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Thesis

Mechanisms of TonB-dependent protein import in Pseudomonas aeruginosa

Abstract:

The rise of multidrug resistance in several bacterial families is an emerging therapeutic crisis, with the potential to revert society to a pre-antibiotic era. Of particular concern is the opportunistic pathogen, Pseudomonas aeruginosa, a major causative agent of hospital-associated infections. As such, the development of novel therapeutics to target multidrug resistant P. aeruginosa is critical. Protein antibiotics synthesised by P. aeruginosa, known as pyocins, have recently become the f...

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Sub department:
Biochemistry
Oxford college:
Queen's College
Role:
Author
ORCID:
0000-0001-8513-7054

Contributors

Role:
Supervisor
ORCID:
0000-0002-3273-0302
Role:
Supervisor
ORCID:
0000-0001-7297-7708
Role:
Supervisor
More from this funder
Programme:
Wellcome Trust Structural Biology
Funding agency for:
Goult, J
Grant:
1797450
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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