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Gradient collagen/nanohydroxyapatite composite scaffold: development and characterization.

Abstract:

This paper reports an in situ diffusion method for the fabrication of compositionally graded collagen/nanohydroxyapatite (HA) composite scaffold. The method is diffusion based and causes the precipitation of nano-HA crystallites in situ. A collagen matrix acts as a template through which calcium ions (Ca(2+)) and phosphate ions (PO4(3-)) diffuse and precipitate a non-stoichiometric HA. It was observed that needle-like prismatic nano-HA crystallites (about 2 x 2 x 20 nm) precipitated in the in...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Materials
Role:
Author
Journal:
Acta biomaterialia
Volume:
5
Issue:
2
Pages:
661-669
Publication date:
2009-02-01
DOI:
EISSN:
1878-7568
ISSN:
1742-7061
Source identifiers:
1873
Language:
English
Keywords:
Pubs id:
pubs:1873
UUID:
uuid:3fe1be07-9ec0-43a4-81a8-4302072b581b
Local pid:
pubs:1873
Deposit date:
2012-12-19

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