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LDL particle size distribution is associated with carotid intima-media thickness in healthy 50-year-old men.

Abstract:

Results of cross-sectional and prospective studies have suggested that small, dense low-density lipoprotein (LDL) particles predispose to coronary heart disease. We investigated the relationships between plasma concentrations of LDL subfractions and intima-media thickness (IMT) of the common carotid artery (CCA), quantified by B-mode ultrasound, in 94 healthy, 50-year-old men, all of whom were homozygous for the apolipoprotein E3 allele. A novel 3% to 7.5% polyacrylamide gradient gel was deve...

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Publication status:
Published

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Publisher copy:
10.1161/01.atv.19.10.2422

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Journal:
Arteriosclerosis, thrombosis, and vascular biology
Volume:
19
Issue:
10
Pages:
2422-2430
Publication date:
1999-10-01
DOI:
EISSN:
1524-4636
ISSN:
1079-5642
Source identifiers:
8248

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