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A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions

Abstract:

Kinesin superfamily proteins are ubiquitous to all eukaryotes and essential for several key cellular processes. With the establishment of genome sequence data for a substantial number of eukaryotes, it is now possible for the first time to analyze the complete kinesin repertoires of a diversity of organisms from most eukaryotic kingdoms. Such a "holistic" approach using 486 kinesin-like sequences from 19 eukaryotes and analyzed by Bayesian techniques, identifies three new kinesin families, tw...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Gull Lab
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Research group:
Gull Lab
Role:
Author
Wellcome Trust More from this funder
Publisher:
American Society for Cell Biology Publisher's website
Journal:
Molecular Biology of the Cell Journal website
Volume:
17
Issue:
4
Pages:
1734 - 1743
Publication date:
2006-04-01
EISSN:
1939-4586
ISSN:
1059-1524
Language:
English
Keywords:
Subjects:
UUID:
uuid:408da9a2-4132-432e-97e8-05c2481d4f51
Local pid:
ora:1517
Deposit date:
2008-03-14

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