Abstract:

Immunosenescence is the progressive loss of immune tissue that result from (i) functional, (ii) clonal or (iii) systemic changes to the cells or tissue that make up the immune system. While this process occurs gradually during the ageing process, there is overwhelming evidence to implicate HIV infection in driving all three aspects of immunosenescence by inducing high levels of immune activation. In the current literature, there is a dearth of data on the impact of HIV-2 infection or untre...

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