The histone deacetylase inhibitor panobinostat as a radiosensitiser in bladder cancer
Muscle invasive bladder cancer (MIBC) has a poor prognosis. Currently, therapy consists of radical radiotherapy or cystectomy with or without chemotherapy. The average age of patients with MIBC is high and older patients are less able to tolerate surgery or chemoradiation due to their impaired physical fitness and generally poor renal function. There is an urgent need to find new treatment regimes that are both tolerable and effective.
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- Oxford University, UK
- Copyright holder:
- Groselj, B
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