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MSL1 is a mechanosensitive ion channel that dissipates mitochondrial membrane potential and maintains redox homeostasis in mitochondria during abiotic stress

Abstract:

Mitochondria must maintain tight control over the electrochemical gradient across their inner membrane to allow ATP synthesis while maintaining a redox-balanced electron transport chain and avoiding excessive reactive oxygen species production. However, there is a scarcity of knowledge about the ion transporters in the inner mitochondrial membrane that contribute to control of membrane potential. We show that loss of MSL1, a member of a family of mechanosensitive ion channels related to the b...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1111/tpj.13301

Authors


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Funding agency for:
Lee, C
Grant:
ALTF 1140-2011
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Funding agency for:
Millar, A
Grant:
FT110100242
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Funding agency for:
Haswell, E
Grant:
2R01GM084211-5A1
Publisher:
Wiley Publisher's website
Journal:
Plant Journal Journal website
Volume:
88
Issue:
5
Pages:
809-825
Publication date:
2016-11-03
Acceptance date:
2016-08-09
DOI:
EISSN:
1365-313X
ISSN:
0960-7412
Source identifiers:
638504
Language:
English
Keywords:
Pubs id:
pubs:638504
UUID:
uuid:4107502b-60a4-4614-b78e-fc370f7c4cfc
Local pid:
pubs:638504
Deposit date:
2016-08-22

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