Journal article
Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.
- Abstract:
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OBJECTIVES: To identify, map, clone, and functionally validate a novel mouse model for impaired glucose tolerance and insulin secretion. RESEARCH DESIGN AND METHODS: Haploinsufficiency of the insulin receptor and associated mild insulin resistance has been used to sensitize an N-ethyl-N-nitrosourea (ENU) screen to identify novel mutations resulting in impaired glucose tolerance and diabetes. The new impaired glucose tolerance 4 (IGT4) model was selected using an intraperitoneal glucose tolera...
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- Publication status:
- Published
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- Publisher copy:
- 10.2337/db07-0337
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Authors
Bibliographic Details
- Journal:
- Diabetes
- Volume:
- 57
- Issue:
- 8
- Pages:
- 2234-2244
- Publication date:
- 2008-08-01
- DOI:
- EISSN:
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1939-327X
- ISSN:
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0012-1797
- Source identifiers:
-
110456
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:110456
- UUID:
-
uuid:411d1c88-0ec9-4b7b-99d2-2d3ac99ee816
- Local pid:
- pubs:110456
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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