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Journal article

Human T cell receptor-mediated recognition of HLA-E.

Abstract:

The HLA-E class Ib molecule presents hydrophobic peptides derived from the leader sequences of other class I molecules, constituting the ligands for CD94/NKG2 lectin-like receptors. Along the course of our studies on human CD94+ T cells, we characterized an alpha beta CD8+CD94/NKG2C+ CTL clone (K14). In cytolytic assays against the murine TAP-deficient RMA-S cells transfected with human beta2 microglobulin and HLA-E (RMA-S/HLA-E), loaded with different synthetic peptides, K14 displayed a patt...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Journal:
European journal of immunology
Volume:
32
Issue:
4
Pages:
936-944
Publication date:
2002-04-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Source identifiers:
131107

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